Senior Research Associate I, Neuroinflammation In Vitro

Company: Takeda Pharmaceutical
Location: La Mesa
Posted on: May 11, 2022

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Senior Research Associate I, Neuroinflammation In Vitro where you will will be part of a Neurogastroenterology team focused on development of neuroinflammation-related in vitro primary cultures (neurons and glia) and assays (cell based & biochemical) and evaluation of assets for drug discovery programs in the therapeutic area of gastrointestinal (GI) diseases. You -will apply expertise in cell pharmacology and biochemistry to contribute to the neuroinflammation in vitro platform and generate key data for small molecules and biologics to support projects. -How you will contribute:

• Establishes, optimizes, and maintains primary in vitro cell cultures and cell lines.
• Develops neuroinflammation relevant in vitro functional assays for target validation using contemporary biochemical and cell based assays with appropriate controls.
• Independently conducts complex experiments within a project scope, exercising judgement to evaluate a variety of technical factors, and obtain optimum solutions.
• Independently provides work group with technical guidance and problem resolution related to methods, procedures, and processes. Prepares and presents technical information at group meetings.
• Generates quality data using in vitro assays with a high level of efficiency; reviews and reports assay results to project teams; may present data/posters to external research or scientific community.
• Expected to organize time and plan specifics of project related work with oversight from manager or project representative.
• Utilizes assigned literature to increase knowledge base and implement improvements.
• Keeps an accurate, comprehensible, concise notebook in accordance with company policy.
• Maintains lab equipment and supplies as needed, maintains a safe and organized lab bench.
• Communicates with colleagues effectively.Minimum Requirements/Qualifications:
  • Requires an MS in a scientific discipline (or equivalent), or a BS degree in a scientific discipline (or equivalent) with 2+ years experience, or Associates degree in a scientific discipline with 4+ years relevant industry experience.
  • Enjoying bench science, scientifically curious, self-motivated, willing and comfortable of spending large amount of time in lab generating data
  • Solid understanding of in vitro assay (Cell based and Biochemistry) development and validation
  • Demonstrated ability to perform experiments and solve technical problems effectively and independently
  • Able to make detailed observations, analyze data, and interpret results in order to suggest, design and pursue relevant experiments with appropriate controls
  • Proficient in general cell culture skills and basic assay techniques (eg. mammalian cell culture, qRT-PCR, Western blot, ELISA, immunocytochemistry).
  • Experience in isolating and culturing primary cells from rodent/human tissues, primary neuron and glia culture experience is preferred.
  • Experience in neuronal/glial function assays is desirable (eg. Ca2+ imaging, MEA, patch, FLIPR)
  • Experience in developing and troubleshooting cell-based assays for increased throughput screeningWhat Takeda can offer you:
    • Comprehensive Healthcare: Medical, Dental, and Vision
    • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
    • Health & Wellness programs including onsite flu shots and health screenings
    • Generous time off for vacation and the option to purchase additional vacation days
    • Community Outreach Programs and company match of charitable contributions
    • Family Planning Support
    • Flexible Work Paths
    • Tuition reimbursementMore about us:At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.Absent an approved religious or medical reason, all US field-based employees must be fully vaccinated for COVID-19, as a condition of employment.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsSan Diego, CAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, La Mesa , Senior Research Associate I, Neuroinflammation In Vitro, Other , La Mesa, California